As the COVID-19 delta variant causes a surge in COVID-19 cases and hospitalizations in the U.S., protests against mandatory COVID vaccines have cropped up around the country.

Dozens of people gathered outside St. John’s Hospital in Maplewood, Minnesota on Saturday to protest vaccination mandates from health care systems including M Health Fairview, Allina Health, HealthPartners and Children’s Minnesota, ABC affiliate KSTP reported.

The only exemptions are for strong religious beliefs or medical conditions.

Hundreds protested outside of ChristianaCare in Newark, Delaware, Saturday to push back against the hospital’s decision to mandate the COVID-19 vaccine for all employees, according to WPVI.

And more than 100 gathered in Vancouver, Washington, to protest COVID-19 vaccine mandates for hospital workers, ABC’s Portland affiliate, KATU reported.

National Institutes of Health Director Dr. Francis Collins said Sunday he believes vaccine requirements could make a difference in slowing the rapid spread of COVID-19 and acknowledged how politics has polarized public opinion on pandemic mitigation strategies.

“Why is it that a mandate about a vaccine or wearing a mask suddenly becomes a statement of your political party? We never should have let that happen.” Collins told ABC’s This Week.

More than 35.7 million Americans have been infected by COVID-19, resulting in over 616,000 deaths as of early Monday, according to data compiled byJohns Hopkins University.